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1. Overview:

Ochratoxin A (OTA) is a toxic metabolite produced by some species of Aspergillus and Penicillium; it is a mycotoxin with high kidney and liver toxicities, and has teratogenic, mutagenic and carcinogenic effects.

2. Principle:

The basis of the measurement is the antigen-antibody reaction. Antibodies are connected to the Ochratoxin A column and the toxins in the sample are extracted, filtered, and passed slowly through the immunoaffinity column. The toxins bind to the antibodies in the column and the immunoaffinity column is then washed to remove other unrelated substances that have not been bound. Ochratoxin A is eluted with methanol, and then injected into the analytical instrument for detection.

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